Research Interest: Application of protein
chip technology into predictive diagnostics of myeloma
B.E. in Biochemistry, East
China Institute of Chemical Technology, Shanghai, China
Ph.D. in Biochemistry and
Molecular Biology, Louisiana State University Medical Center, New Orleans, LA
Postdoctoral Research
Associate, Department of Medicine, University of Arkansas for Medical Sciences
Research Molecular Oncologist,
Division of Hematology/Oncology, Arkansas Cancer Research Center, University of
Arkansas for Medical Sciences
Postdoctoral Fellow, Division
of Genetic Toxicology, National Center for Toxicological Research, Pine Bluff,
Arkansas
Research Instructor, Department
of Medicine, University of Arkansas for Medical Sciences
Selected Publications:
SM. Jazwinski, JB Chen. and J.
Sun. (1993) A single gene change can extend yeast life span: the role of Ras in
cellular senescene. Advances in Experimental Medicine & Biology. Vol.330:45-53
James B. Chen and Joshua
Epstein. (1996) Circulating clonal lymphocytes in myeloma constitute a minor
subpopulation of B cells. Blood, Vol.87:1972-1976
James B. Chen, S. Bala Dass,
Dan Casciano and R.Heflich. (1998) Sensitivity of the X 174 am3 allele
in relation to the Endogenous hprt Gene for detecting of mutation in
transgenic mice. Environmental and Molecular Mutagenesis, 32:229-235
R. Delonchamp, H. Malling, J.
Chen and R. Heflich.(1999) An estimator of the mutant frequency in assays using
transgenic animals. Mutation Research. Mutation Research. 440 (1): 101-8
James B. Chen, Vasily N.
Dobrovolsky and Robert H. Heflich. (1999) Development of a mouse embryonic
fibroblast cell line containing the X 174 am3 allele as a target for
detecting mutation. Mutation Research, 444: 347-353
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